Abstract: Flexible piezoresistive pressure sensors have the advantages of mechanical flexibility, wearable, low fabrication cost, and sensitivity can be optimized through structural design. These characteristics make them of important application value in health detection, robot tactile perception and shape recognition. However, sensors still face problems such as energy drive, environmental interference and reuse in practical application. Researchers have carried out a lot of work and achieved some innovative research results around these directions. Compared with the structural design to constantly update the upper limit of sensor sensitivity, it is the future development trend to improve the comprehensive performance of sensor in line with practical application. This paper reviews the common applications of flexible piezoresistive pressure sensors in daily life, and looks forward to the future development direction in view of the existing problems in application, and introduces the progress of related work in recent years.